Evidence for gene conversion among immunoglobulin heavy chain variable region genes.
نویسندگان
چکیده
منابع مشابه
Evidence for gene conversion among immunoglobulin heavy chain variable region genes
We have previously reported that the VH region amino acid sequence of a phosphocholine (PC)-binding hybridoma antibody of CBA/J origin, HP101 6G6 (6G6), differs extensively from the VH regions of other PC-binding antibodies. The sequence of 6G6 VH appears to be derived from a gene homologous to the BALB/c V11 gene, a member of the PC VH (T15 VH) gene family not normally used to encode PC-bindin...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1984
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.159.3.773